ESC Congress 2025: prevention takes center stage
Originally published on explorishealth.com

ESC Congress 2025 in Madrid had a clear focus: prevention.
New scientific findings and technologies are changing how we understand risk and act clinically. Our key takeaways:
- Inflammation and "invisible risk": hs-CRP is gaining importance as an independent predictor, especially in patients without classic risk factors.
- Genetics: polygenic risk scores open up new ways of stratifying risk, especially in younger patients.
- Imaging and AI: AI-based evaluation of routine CCTA changes treatment decisions, with potential for personalized prevention.
- New therapies: the focus is shifting from lipid management to targeted pathway modulation, for example via IL-6 and Lp(a).
- Adoption and integration: evidence alone is not enough; embedding it in existing workflows is crucial.
Our conclusion: prevention is becoming a multi-layered approach that combines inflammation, genetics, imaging and AI. The next step is clear use cases and thresholds that physicians can act on every day.
Interested in how Cardio Explorer® applies to your coronary pathway? Our team is happy to walk you through the platform and the evidence behind it.



